17β-Estradiol *Sigma货号：E8875-1

一般描述

β-Estradiolis a natural steroid estrogen[1] and a female sex hormone.[2] It is an essential component of the female menstrual cycle and plays an important role in the growth and maintenance of the reproductive system.[2] 应用
β-雌二醇已用于：
牛卵丘卵母细胞复合体（COC）的体外成熟[3]
作为可用作对照培养基的体外成熟培养基（IVM）中的一种补充剂[4]
雌激素诱导试验[5]

生化/生理作用

The main estrogen secreted by premenopausal ovaries
estrogen guides embryogenesis and the development of puberty female phenotype by regulating gene transcription and therefore protein synthesis
It also induces the production of gonadotropin, which in turn induces ovulation
Exposure to estradiol will increase the incidence and proliferation of breast cancer