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- 详细信息
- 技术资料
- 标记物:
Unconjugated
- 适应物种:
Human
- 供应商:
武汉恩玑生命科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 规格:
50uL/100uL
| 规格: | 50uL | 产品价格: | ¥1350.0 |
|---|---|---|---|
| 规格: | 100uL | 产品价格: | ¥2250.0 |
产品概述
产品性能
免疫原
产品应用
研究背景
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP (PubMed:28028151, PubMed:22461490). During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC . Required for CD4+ T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane (PubMed:28028151). Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing (PubMed:25762780).
研究领域
Cardiovascular
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