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- PEH1074
- 2025年07月12日
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- 详细信息
- 技术资料
- 英文名：
Leptin
- 供应商：
武汉恩玑生命科技有限公司
- 规格：
10ug/50ug/500ug
| 规格： | 10ug | 产品价格： | ￥180.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥360.0 |
| 规格： | 500ug | 产品价格： | ￥1000.0 |
| 产品名称 |
Recombinant Human Leptin |
| 英文名称 |
Leptin |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Leptin is produced by our E.coli expression system and the target gene encoding Val22-Cys167 is expressed. |
| Accession |
P41159 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
16.1 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,50mM NaCl,10%Trehalose,0.02%Tween 80,pH8.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Leptin; Obese Protein; Obesity Factor; LEP; OB; OBS |
| 背景介绍 |
| Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
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