Recombinant Rat PSD-95 (N-6His)

Recombinant Rat PSD-95 (N-6His

)
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  • ¥760 - 10980
  • EnkiLife
  • PER0537
  • 2025年11月14日
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    • 详细信息
    • 技术资料
    • 英文名

      Disks large homolog 4/DLG4/PSD95

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥760.0
    规格:50ug产品价格:¥2280.0
    规格:500ug产品价格:¥10980.0
    产品名称

    Recombinant Rat PSD-95 (N-6His)

    英文名称

    Disks large homolog 4/DLG4/PSD95  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Rat Postsynaptic Density Protein 95 is produced by our E.coli expression system and the target gene encoding Met1-Leu724 is expressed with a 6His tag at the N-terminus.

    Accession

    NP_062567

    表达宿主

    E.coli

    种属

    Rat

    预测分子量

    81.9 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM EDTA, 1mM DTT, pH7.5.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Disks large homolog 4; Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90; PSD95; DLG4

     

    背景介绍
    Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain,3 PDZ (DHR) domains and 1 SH3 domain. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. DLG4 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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