Recombinant Human TNF RII (C-Fc)

Recombinant Human TNF RII (C-F

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  • ¥690 - 10980
  • EnkiLife
  • PHH1746
  • 2025年11月15日
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    • 详细信息
    • 技术资料
    • 英文名

      TNF RII/TNFRSF1B/CD120b/TNFR2/TNF Receptor II/Tumor Necrosis Factor Receptor II

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥690.0
    规格:50ug产品价格:¥1800.0
    规格:500ug产品价格:¥10980.0
    产品名称

    Recombinant Human TNF RII (C-Fc)

    英文名称

    TNF RII/TNFRSF1B/CD120b/TNFR2/TNF Receptor II/Tumor Necrosis Factor Receptor II  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a human IgG1 Fc tag at the C-terminus.

    Accession

    P20333

    表达宿主

    Human Cells

    种属

    Human

    预测分子量

    51.9 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Tumor necrosis factor receptor superfamily member 1B; TNFRSF1B; Tumor necrosis factor receptor 2; TNF-R2; TNF-RII; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b

     

    背景介绍
    Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressed predominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as on endothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, and mesenchymal stem cells.TNF RII binds to the membranebound forms of TNFα and Lymphotoxinα/TNFβ;soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNF biological activity by binding TNF thereby preventing it from activating membrane TNF receptors.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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