Recombinant Human BIRC5

Recombinant Human BIRC5

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  • ¥690 - 10980
  • EnkiLife
  • PEH0132
  • 2025年11月14日
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    • 详细信息
    • 技术资料
    • 英文名

      Baculoviral Iap Repeat-Containing Protein 5/Birc5

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥690.0
    规格:50ug产品价格:¥1800.0
    规格:500ug产品价格:¥10980.0
    产品名称

    Recombinant Human BIRC5

    英文名称

    Baculoviral Iap Repeat-Containing Protein 5/Birc5  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.

    Accession

    O15392

    表达宿主

    E.coli

    种属

    Human

    预测分子量

    16.4 KDa

    制剂

    Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 7.5.

    运输方式

    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

    Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    分子别名
    Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; BIRC5; API4; IAP4

     

    背景介绍
    Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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