Recombinant Human ENO1 (C-6His)

Recombinant Human ENO1 (C-6His

)
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  • ¥1080 - 12200
  • EnkiLife
  • PEH1893
  • 2025年11月14日
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  • 企业认证

    • 详细信息
    • 技术资料
    • 英文名

      Enolase 1/ENO1/Alpha-enolase/MPB-1/NNE

    • 供应商

      武汉恩玑生命科技有限公司

    • 规格

      10ug/50ug/500ug

    规格:10ug产品价格:¥1080.0
    规格:50ug产品价格:¥3180.0
    规格:500ug产品价格:¥12200.0
    产品名称

    Recombinant Human ENO1 (C-6His)

    英文名称

    Enolase 1/ENO1/Alpha-enolase/MPB-1/NNE  

    纯度

    Greater than 95% as determined by reducing SDS-PAGE

    内毒素

    <1 EU/µg as determined by LAL test.

    蛋白构建

    Recombinant Human Alpha-enolase is produced by our E.coli expression system and the target gene encoding Met1-Lys434 is expressed with a 6His tag at the C-terminus.

    Accession

    P06733

    表达宿主

    E.coli

    种属

    Human

    预测分子量

    48 KDa

    制剂

    Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 250mM NaCl, 1mM MgSO4, 20% Glycerol, 5% Trehalose, 5% Mannitol, 0.02% Tween80, pH 7.5.

    运输方式

    The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

    稳定性&储存

    Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

    复溶

     

    分子别名
    Alpha-enolase;2-phospho-D-glycerate hydro-lyase;C-myc promoter-binding protein;Enolase 1;MBP-1;MPB-1;Non-neural enolase;NNE;Phosphopyruvate hydratase;Plasminogen-binding protein;ENO1

     

    背景介绍
    Alpha-enolase, also known as MPB-1, NNE, Enolase 1, belongs to the enolase family. Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding. Isoform MBP-1 interacts with TRAPPC2B. ENO1 interacts with ENO4 and PGAM2. The alpha/alpha homodimer of ENO1 is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells. Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses and may also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. ENO1 also stimulates immunoglobulin production.

     

    注意事项

    本司产品仅用于科研,不用于临床诊断和治疗

     

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