FGR抗体;FGR Polyclonal Antibody

Description FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr vi r us results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. References 1. Immunity. 2005 Feb;22(2):235-46. 2. Biochemistry. 2007 Oct 2;46(39):11023-32. Specification Aliases:SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr Entrez GeneID:2268 Swissprot:P09769 clone:6G2 WB Predicted band size:56kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human FGR expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 IHC:1/200 - 1/1000 ELISA:1/10000