FOXP3抗体;FOXP3 Polyclonal Antib

Description The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. References 1. Roncador G et al. Eur J Immunol. 2005. 35:1681-1691.2. Yisong YW. PNAS. 2005 102 (14): 5126-5131. Specification Aliases:JM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3 Entrez GeneID:50943 Swissprot:Q9BZS1 clone:2A11G9 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human,Mouse Immunogen:Purified recombinant fragment of human Foxp3 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application IHC:1/200 - 1/1000 ICC:1/200 - 1/1000 ELISA:1/10000