HDAC2抗体;HDAC2 Polyclonal Antib

Description This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. References 1.Zhonghua Bing Li Xue Za Zhi. 2012 Jul;41(7):466-9. 2.J Cell Biochem. 2012 Jun;113(6):2167-77. Specification Aliases:HD2; RPD3; YAF1 Entrez GeneID:3066 Swissprot:Q92769 clone:4C10C3 WB Predicted band size:55.4kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human HDAC2 (AA: 217-327) expressed in E. Coli. Formulation:Purified antibody in PBS with 0.05% sodium azide Application ELISA:1/10000