ZBTB16抗体;ZBTB16 Polyclonal Ant

Description This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung. References 1. Cancer Res. 2008 Apr 15;68(8):2745-54 2. Immunity. 2008 Sep 19;29(3):391-403. Specification Aliases:PLZF; ZNF145; ZBTB16 Entrez GeneID:7704 Swissprot:Q05516 clone:5B3 WB Predicted band size:74kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human ZBTB16 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application WB:1/500 - 1/2000 ICC:1/200 - 1/1000 ELISA:1/10000