GRIA3抗体;GRIA3 Polyclonal Antib

Description Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. References 1. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):468-76. 2. Am J Med Genet A. 2009 Jun;149A(6):1280-9. Specification Aliases:GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3 Entrez GeneID:2892 Swissprot:P42263 clone:1D2 WB Predicted band size:101kDa Host/Isotype:Mouse IgG1 Antibody Type:Primary antibody Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. Species Reactivity:Human Immunogen:Purified recombinant fragment of human GRIA3 expressed in E. Coli. Formulation:Ascitic fluid containing 0.03% sodium azide. Application IHC:1/200 - 1/1000 ELISA:1/10000