- ￥600 - 3200
- 上海莼试
- CS-01Y68019
- 国产
- 2025年07月12日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
21
- 英文名：
Dimethyl DL-Glutamate (hydrochloride)
- CAS号：
13515-99-6
- 供应商：
上海莼试
- 保存条件：
Store at -20°C
- 规格：
5g 10g 25g 50g
| 货号 | CS-01Y68019 | 规格 | 5g 10g 25g 50g |
| CAS号 | 13515-99-6 | 分子量 | 211.6 |
| 含量 | >98.00% | 别名 | Glutamic Acid dimethyl ester,Dimethyl 2-aminopentanedioate |
| 分子式 | C7H13NO4 • HCl | 化学名 | 1,5-dimethyl ester glutamic acid, monohydrochloride |
| 产地 | 国产 | 用途 | 仅供科研研究实验 |
分子式:C7H13NO4 • HCl
分子量:211.6
溶解度:≤5mg/ml in ethanol;10mg/ml in DMSO;15mg/ml in dimethyl formamide
储存条件:Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
Dimethyl DL-glutamate is a cell-permeable form of glutamate.Extracellular glutamic acid is an excitatory neurotransmitter, while intracellular glutamic acid is an amino acid that serves various metabolic roles.In vitro: Dimethyl DL-glutamate at 3.0-10.0 mM could enhance insulin release evoked by 6.0-8.3 mM D-glucose, 1.0-10.0 mM L-leucine, or 5.0-10.0 mM 2-amino-bicyclo(2,2,1)heptane-2-carboxylic acid, resulting in a shift to the left of the sigmoidal relationship between insulin output and D-glucose concentration. Moreover, dimethyl DL-glutamate unmasked the insulinotropic potential of glibenclamide in the ance of D-glucose. In islets exposed to L-leucine, the insulinotropic action of dimethyl DL-glutamate coincided with an early fall and later increase in 86Rb outflow. In addition, the overall gain in O2 uptake represented the balance between dimethyl DL-glutamate oxidation and its sparing action on the catabolism of endogenous fatty acids and exogenous D-glucose [1].In vivo: Dimethyl DL-glutamate was intravenously administered as a primed constant infusion to adult rats that had been injected with streptozotocin during the neonatal period. Results showed that dimethyl DL-glutamate augmented plasma insulin concentration and potentiated and/or prolonged the insulinotropic action of GLP-1 injected intravenously at min 5 of the test [2].Clinical trial: So far, no clinical study has been conducted.
注意事项：
抗逆滴加序列
每次向板内滴加抗原时，移液器滴头要与平面45度悬空，不要触碰到孔内的液体，由后向前依次滴加(即浓度由低往高滴加)。
抗感染反应期
抗原抗体在室温20~25℃下，必须反应30min以上，若环境温度低于室温，可将微量反应板置于恒温培养箱中，使二者充分反应。
旅游温度
磷酸盐缓冲液的pH值要在高压灭菌后进行滴定，往往在高压后pH值会有所改变，所以高压后再调一次pH值更为准确。磷酸盐缓冲液一经使用保存期不要超过3周。当pH<5.8时，红细胞会产生自凝现象;当pH>7.8时，图形洗脱加快，易造成肉眼观察产生误差;p H=7.2时，红细胞沉降最充分，图形最清晰。
当滴注 1%红细胞悬液时，应经常摇晃红细胞悬液，使红细胞均匀地分布在磷酸缓冲液中，以防止红细胞下降。
反应时间及温度
加入鸡红血球之后，反应板在室温(20~25℃)静置30~40min，对照孔血球下沉于孔底，即可判定结果。若室温达不到实验要求，需相应调整反应时间。当环境温度低于4℃时，红细胞发生自凝;高于37℃时，会发生反应物分离和红细胞溶血。
使用方法：
1.本蛋白酶抑制剂混合物为100×的储存液，使用时按照1:100的比例加入到裂解液中(例如，1ml裂解液中加入10μl蛋白酶抑制剂混合物)，混匀后即可使用。根据需要，0.5M的EDTA也按照1:100的比例加入到裂解液中（如用于检测金属蛋白酶活性，则不宜添加EDTA）。含有蛋白酶抑制剂混合物的裂解液宜现用现配，不宜配制后冻存待后续使用。
2. 待所需的抑制剂添加完毕混匀后，就可以开始进行哺乳动物组织的裂解和蛋白提取。
公司正在出售的产品：
| Recombnant Moue Endocan proten , C- H Tag | TP63 Antibody Blocking Peptide |
| Recombinant Human AMT | Recombinant Human NCF1 |
| phospho-RUNX3 (Ser338) Antibody Blocking Peptide | Recombinant Human Nck |
| CC85C Antibody Blocking Peptide | Recombinant Human NCS1 |
| PRSS16 Antibody Blocking Peptide | Recombinant Human Nck-2 |
| CCR2 Antibody Blocking Peptide | Recombinant Human NDE1 |
| Syntaxin 1A(brain) Antibody Blocking Peptide | Recombinant Human NDEL1 |
| HIP1R Antibody Blocking Peptide | 19号染色体开放阅读框38/HDE1封闭多肽 |
| PTPN6 Antibody Blocking Peptide | Recombinant Human NCE2 |
| Phospho-PIM1 (Tyr218) Antibody Blocking Peptide | Recombinant Human NCALD |
| P4HTM Antibody Blocking Peptide | Recombinant Human Natriuretic Peptide Receptor A |
| ANGPT4 Antibody Blocking Peptide | Recombinant Human NAT1 |
| Caspase-6 Antibody Blocking Peptide | Dimethyl DL-Glutamate (hydrochloride)Recombinant Human NARS |
| SLC4A1AP Antibody Blocking Peptide | Recombinant Human NAPSIN A |
| FOXK1 Antibody Blocking Peptide | Recombinant Human NAPG |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Automated Trace Analysis of Pesticides in Water
PDA/PCD/FLD. The PDA detector is used as a general-purpose detector; the FLD is useful for confirmation of N -methyl-carbamate and N -methyl-carbamoyloxime pesticides, which are postcolumn derivatized with o -phthalaldehyde and N,N -dimethyl
Synthesis of Peptidomimetic Conjugates of Cyclic Nucleoside Phosphonates
) Triethylamine (Et 3 N; Aldrich), freshly distilled over KOH 3‐(Ethyliminomethyleneamino)‐N,N ‐dimethyl‐propan‐1‐amine hydrochloride (EDC⋅HCl; Aldrich
Measurement of Cation Movement in Primary Cultures Using Fluorescent Dyes
): e.g., 1 mM glutamate, glycine, or N ‐methyl‐D‐aspartate (NMDA) in HEPES buffer 35‐mm disposable plastic culture dishes
技术资料暂无技术资料 索取技术资料
