IL-3RA, Human, Recombinant

IL-3RA, Human, Recombinant

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  • ¥1380 - 25680
  • Procell
  • PCK075
  • 武汉
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      IL-3RA, Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1380.0
    规格:50ug产品价格:¥3680.0
    规格:500ug产品价格:¥17480.0
    规格:1mg产品价格:¥25680.0

    产品信息

    别名Interleukin-3 Receptor subunit alpha; IL-3 Receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA
    物种Human
    表达宿主Human Cells
    序列信息Thr19-Arg305
    检索号P26951
    分子量60 kDa
    表观分子量80-100kDa

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    CD123, also known as Interleukin-3 Receptor subunit alpha, belongs to the type I Cytokine Receptor family. In mouse, there are two classes of high-affinity IL3 Receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF Receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage-committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL-3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric Receptor complex.

    IL-3RA, Human, Recombinant

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