IL-15RA/ CD215 (C-Fc), Human, Recombinant

IL-15RA/ CD215 (C-Fc), Human,

Recombinant
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  • ¥1780 - 27980
  • Procell
  • PCK149
  • 武汉
  • 2025年07月16日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      IL-15RA/ CD215 (C-Fc), Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1780.0
    规格:50ug产品价格:¥4980.0
    规格:500ug产品价格:¥18980.0
    规格:1mg产品价格:¥27980.0

    产品信息

    别名CD215; IL15RA; CD215 antigen; IL-15 Receptor subunit alpha; IL-15RA; IL-15R-alpha; Interleukin 15 Receptor; alpha; Interleukin-15 Receptor subunit alpha; MGC104179
    物种Human
    表达宿主Human Cells
    序列信息Ile31-Thr172
    检索号Q13261-3
    分子量42.2 kDa
    表观分子量60-75 kDa
    标签C-Fc
    生物活性Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.35-3.5 ng/ml.

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glyco Protein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” Cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/ IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 Receptor β and γ heterodimers and enables signaling to cells.

    IL-15RA/ CD215 (C-Fc), Human,

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