PDGF-BB/ PDGF2, Human, Recombinant

PDGF-BB/ PDGF2, Human, Recombi

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  • ¥1780 - 25680
  • Procell
  • PCK067
  • 武汉
  • 2025年07月14日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      PDGF-BB/ PDGF2, Human, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1780.0
    规格:50ug产品价格:¥4980.0
    规格:500ug产品价格:¥17480.0
    规格:1mg产品价格:¥25680.0

    产品信息

    别名PDGFBB; PDGF-BB
    物种Human
    表达宿主E.coli
    序列信息Ser82-Thr190
    检索号P01127
    分子量12.42 kDa
    表观分子量14 kDa
    生物活性Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml.

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/ VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its Receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

    PDGF-BB/ PDGF2, Human, Recombi

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