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Recombinant Mouse ALCAM (C-6Hi

s)
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  • ¥1200 - 3520
  • 近岸蛋白(Novoprotein)
  • C34B
  • 国产
  • 2026年04月27日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 英文名

      Recombinant Mouse ALCAM

    • CAS号

    • 保质期

      一年

    • 供应商

      上海经科化学科技有限公司

    • 保存条件

      -20℃

    • 规格

      10ug/50ug

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    产品描述
    Recombinant Mouse CD166 antigen is produced by our Mammalian expression system and the target gene encoding Trp28-­Lys527 is expressed with a 6His tag at C-terminus.
     
    蛋白编号
    Q61490
     
    产品别称
    CD166 antigen; Activated leukocyte cell adhesion molecule; CD166; ALCAM; MEMD
     
    分子量
    57 KDa
     
    表观分子量
    65-115 KDa, reducing conditions
     
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4
     
    内毒素
    < 1 EU/µg as determined by LAL test.
     
    纯度-SDS-PAGE
    产品细节图片1
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
     
    生物活性-BLI
    产品细节图片2Loaded Recombinant Mouse CD6 (C-6His) (Cat#CU62) on SA Biosensor, can bind Recombinant Mouse ALCAM (C-6His) (Cat#C34B) with an affinity constant of 0.195 μM as determined in BLI assay. (Regularly tested)
     
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
     
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
     
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months.
     
    产品背景
    Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM is expressed on thymic epithelium, microvascular endothelium, activated lymphocytes and monocytes, and monocytederived dendritic cells. ALCAM mediates low-affinity adhesion with itself or the cysteine-rich scavenger receptor CD6 to regulate T cell development, immunological synapses(IS), and cell migration through endothelial junctions. ALCAM on thymic epithelia mediates adhesion to CD6 on CD4+CD8+ T cells. Adhesion of ALCAM expressing antigen presenting cells and CD6-expressing T cells stabilizes the early IS, while later it enhances CD3 effects on T cell proliferation, CD25 expression, and Th1 commitment. ALCAM may influence expression or adhesion of the neuronal adhesion molecule NCAML1, both in the developing retina and invasive melanoma.

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    图标文献和实验
    该产品被引用文献

    Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM is expressed on thymic epithelium, microvascular endothelium, activated lymphocytes and monocytes, and monocytederived dendritic cells. ALCAM mediates low-affinity adhesion with itself or the cysteine-rich scavenger receptor CD6 to regulate T cell development, immunological synapses(IS), and cell migration through endothelial junctions. ALCAM on thymic epithelia mediates adhesion to CD6 on CD4+CD8+ T cells. Adhesion of ALCAM expressing antigen presenting cells and CD6-expressing T cells stabilizes the early IS, while later it enhances CD3 effects on T cell proliferation, CD25 expression, and Th1 commitment. ALCAM may influence expression or adhesion of the neuronal adhesion molecule NCAML1, both in the developing retina and invasive melanoma.

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    文献支持
    Recombinant Mouse ALCAM (C-6His)
    ¥1200 - 3520