- ￥3870 - 25190
- Sino Biological
- 北京
- 50010-M03H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/100.00 µg/200.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥25190.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥3870.0 |
| 规格： | 200.00 µg | 产品价格： | ￥3870.0 |
PD-L1/B7-H1重组蛋白|Recombinant Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)（产品说明）
蛋白名称：Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Thr 238) of mouse PD-L1 (NP_068693.1) was fused with the C-terminal His-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to bind mouse PD-1 in functional ELISA.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Phe 19
蛋白分子量：The recombinant mouse PD-L1/Fc is a disulfide-linked homodimeric protein after proteolytic removal of the signal peptide. The reduced monomer consists of 468 amino acids and predicts a molecular mass of 52.8 kDa. As a result of glycosylation, the apparent molecular mass of mouse PD-L1/Fc monomer is approximately 64-90 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_068693.1
蛋白氨基酸序列：Met1-Thr238
蛋白标签：C-human IgG1-Fc & His
蛋白名称：Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His & Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Thr 238) of mouse PD-L1 (NP_068693.1) was fused with the C-terminal His-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to bind mouse PD-1 in functional ELISA.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Phe 19
蛋白分子量：The recombinant mouse PD-L1/Fc is a disulfide-linked homodimeric protein after proteolytic removal of the signal peptide. The reduced monomer consists of 468 amino acids and predicts a molecular mass of 52.8 kDa. As a result of glycosylation, the apparent molecular mass of mouse PD-L1/Fc monomer is approximately 64-90 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_068693.1
蛋白氨基酸序列：Met1-Thr238
蛋白标签：C-human IgG1-Fc & His
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文献和实验该产品被引用文献
1, Miao, X; et al. PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin. Scientific reports, PMID: 29371688
2, Zhao, P; et al. Depletion of PD-1-positive cells ameliorates autoimmune disease. Nature biomedical engineering, PMID: 30952980
3, Yi, M; et al. The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1. Journal of hematology & oncology, PMID: 33593403
2, Zhao, P; et al. Depletion of PD-1-positive cells ameliorates autoimmune disease. Nature biomedical engineering, PMID: 30952980
3, Yi, M; et al. The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-β and PD-L1. Journal of hematology & oncology, PMID: 33593403
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Sino Biological 小鼠PD-L1/B7-H1重组蛋白 His & Fc标签 pd-l1蛋白
￥3870 - 25190
