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- 保存条件：
at-20℃
- 库存：
99
- 抗体英文名：
Anti-DNA Monoclonal antibody (79)
- 规格：
50-100ug
小鼠抗DNA单克隆抗体(克隆号79)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
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文献和实验CD79a/CD79b 分子 CD79a 常用单克隆抗体或代号： Iga ,mb- 1 主要表达细胞： B [B] 分子质量(kDa)和结构： 33(IgSF) 功 能： BCR复合体组成成分 CD79b 常用单克隆抗体或代号： Igb ,B29 主要表达细胞： B [B] 分子质量(kDa)和结构： 39(IgSF) 功 能： BCR复合体组成成分
CD79 α／ CD79 β 白细胞分化抗原及其功能 Igα／Igβ 又称CD79α／CD79β，胞膜外区结构属IgSF，分别有1个C2样区和V样结构域，跨膜区都有一个谷氨酸。两个CD79a／CD79b异二聚体与一个mlg构成B细胞抗原识别受体(BCR)。CD79a和CD79b跨膜区带负电的谷氨酸或谷氨酰胺与mlgM重链跨膜区带正电的氨基酸可形成盐桥，稳定BCR复合物。两种CD79分子的胞质区均有一个ITAM，介导由BCR途径的信号转导。该类CD
V79 Cytotoxicity Test for Membrane Damage
The cytotoxic effect of test chemicals in V79 cell culture can be determined by assessing damage to the plasma membrane as determined by a nucleic acid leakage assay.
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