- ￥2570 - 16740
- Sino Biological
- 北京
- 10443-H08H
- 2026年01月26日
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- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human C-MPL Protein (His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
50 µg/500 µg
| 规格： | 50 µg | 产品价格： | ￥2570.0 |
|---|---|---|---|
| 规格： | 500 µg | 产品价格： | ￥16740.0 |
TPO-R重组蛋白|Recombinant Human C-MPL Protein (His Tag)（产品说明）
蛋白名称：Human C-MPL Protein (His Tag)
蛋白构建：A DNA sequence encoding the Human MPL (P40238-1) (Met1-Trp491) was expressed with a polyhistidine tag at the C-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
蛋白活性：1. Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) captured on Protein A chip can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 12.3 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 2. Loaded Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) on ProA Biosensor, can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 9.06 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method.
预测N端：Gln 26
蛋白分子量：The recombinant Human MPL consists of 477 amino acids and predicts a molecular mass of 54 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P40238-1
蛋白氨基酸序列：Met1-Trp491
蛋白标签：C-His
蛋白名称：Human C-MPL Protein (His Tag)
蛋白构建：A DNA sequence encoding the Human MPL (P40238-1) (Met1-Trp491) was expressed with a polyhistidine tag at the C-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
蛋白活性：1. Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) captured on Protein A chip can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 12.3 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 2. Loaded Recombinant Human TPO/Thrombopoietin Protein, hFc Tag (Cat. No. 10381-H02H) on ProA Biosensor, can bind Recombinant Human TPO-R Protein, His Tag (Cat. No. 10443-H08H) with an affinity constant of 9.06 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method.
预测N端：Gln 26
蛋白分子量：The recombinant Human MPL consists of 477 amino acids and predicts a molecular mass of 54 kDa. It migrates as an approximately 68 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号：P40238-1
蛋白氨基酸序列：Met1-Trp491
蛋白标签：C-His
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文献和实验相关实验
)、干细胞生长因子(SCF)、血小板生成素 (TPO)等。 5、趋化因子(chemokine) 主要功能是招募血液中的单核细胞、中性粒细胞、淋巴细胞等进入特定的淋巴器官和组织以及感染发生的部位。根据趋化因子近N端半胱氨酸(Cys)的位置、排列方式和数量，可分为CC、CXC、C、CX3C四个亚家族。 6生长因子(growth factor，GF) 生长因子(GF)是具有刺激细胞生长作用的细胞因子。 五、细胞因子的生物学活性 1.介导自然免疫、参与抗肿瘤和抗感染 2.调节T、B
-CSF)、多能细胞集落刺激因子(multi-CSF或IL-3)、红细胞生成素（EPO）、干细胞生长因子（SCF）、血小板生成素（TPO）,他们主要促进不同类型血细胞的增值、分化。其中G-CSF、GM-CSF、EPO基因工程产品已作为正式药品进入市场。其他几种因子也在进行临床实验研究，并将陆续进入市场。此类因子在癌症中主要用于防止和对抗放疗、化疗造成各种血细胞的下降。近期，在体外用GM-CSF与IL-4、TNF-a协同扩增树突状细胞，富集抗原后作为肿瘤疫苗，临床研究已显示出良好应用前景。 六、 影响肿瘤
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Sino Biological TPO-R重组蛋白 高纯度 血小板生成素(tpo)重组蛋白
￥2570 - 16740
