TPOR (phospho-Tyr626)  rabbit pAb

TPOR (phospho-Tyr626) rabbit

pAb
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  • ¥900
  • AAB
  • 上海
  • A22782
  • 2025年07月12日
  • WB
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      Synthesized phosho peptide around human TPOR (Tyr626)

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB

    • 浓度

      1 mg/ml

    • 靶点

      MPL TPOR

    • 抗体英文名

      TPOR (phospho-Tyr626) rabbit pAb

    • 抗体名

      TPOR (Tyr626)

    • 规格

      50ul

    MPL proto-oncogene, thrombopoietin receptor(MPL) Homo sapiens In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important

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