- ￥900
- AAB
- 上海
- A21535
- 2025年07月14日
- WB
- Rabbit
- Human, Mouse
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- 详细信息
- 技术资料
- 免疫原：
Synthesized peptide derived from human SIG12
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human, Mouse
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1 mg/ml
- 靶点：
SIGLEC12 SIGLECL1 SLG UNQ9215/PRO34042
- 抗体英文名：
SIG12 rabbit pAb
- 抗体名：
SIG12
- 规格：
50ul
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
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SIG12 rabbit pAb
￥900
