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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
WB,ELISA
- 浓度:
1 mg/ml
- 靶点:
PIK3C2G
- 抗体英文名:
PI 3-Kinase C2γ rabbit pAb
- 抗体名:
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
- 规格:
50ul
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文献和实验Measurement of Phosphoinositide 3-Kinase Activity
The term “PI 3-kinase” is now applied to a growing family of proteins that are able to convert phosphatidylinositol (PtdIns), PtdIns(4)P and PtdIns(4,5)P 2 into PtdIns(3)P, PtdIns(3,4)P 2 and PtdIns(3,4,5)P 3
Measurement of Phosphatidylinositol (PI) Hydrolysis in Activated T Lymphocytes
T-cell activation by antigen-receptor ligation results in rapid activation of phospholipase-Cγ1 (PLC). Activated PLC hydrolyzes membrane inositol phospholipids (PIP 2 ) generating two second messengers: inositol(1,4,5)tris phosphate (IP
294002 competitively inhibits ATP binding to the catalytic subunit of PI 3-kinases and does not inhibit PI 4-kinase, DAG-kinase, PKC, PKA, MAPK, S6 kinase, EGFR or c-src tyrosine kinases and rabbit kidney ATPase. lxj46 信号通路的激活大多通过磷酸化状态
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