- ￥900
- AAB
- 上海
- A19783
- 2025年07月07日
- WB,IHC-p
- Mouse
- Human
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- 详细信息
- 技术资料
- 免疫原：
Synthetic Peptide of Phospho-Akt (S473) at AA range of 410-490
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Monoclonal
- 适应物种：
Human
- 保质期：
1年
- 宿主：
Mouse
- 应用范围：
WB,IHC-p
- 浓度：
1 mg/ml
- 靶点：
AKT1
- 抗体英文名：
Phospho-Akt (S473) mouse mAb(7F9)
- 抗体名：
AKT1
- 规格：
50ul
AKT serine/threonine kinase 1(AKT1) Homo sapiens The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
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Phospho-Akt (S473) mouse mAb(7F9)
￥900
