HJURP rabbit pAb

HJURP rabbit pAb

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  • ¥900
  • AAB
  • 上海
  • A15769
  • 2025年07月15日
  • WB,ELISA
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      Synthesized peptide derived from human protein . at AA range: 80-160

    • 形态

      Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      HJURP FAKTS FLEG1 URLC9

    • 抗体英文名

      HJURP rabbit pAb

    • 抗体名

      Holliday junction recognition protein (14-3-3-associated AKT substrate) (Fetal liver-expressing gene 1 protein) (Up-regulated in lung cancer 9)

    • 规格

      50ul

    function:Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.,sequence caution:Translated as Arg.,subcellular location:Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.,subunit:Interacts with CENPA (via CATD domain); the interaction is direct and specific for CENPA since it does not interact with H3.1- or H3.3-containing nucleosomes. Interacts with 14-3-3 family members in a phosphorylation-dependent manner. Interacts with MSH5 and NBN.,tissue specificity:According to PubMed:17256767 highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411 highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung.,

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