LY-503430,625820-83-9

LY-503430 产品活性：LY-503430 是一种具有口服活性的 AMPA 受体正变构调节剂。LY-503430 可用于研究帕金森病。 产品来源： www.medchemexpress.cn/ly-503430.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：iGluR In Vitro: The submicromolar concentrations of LY-503430 (0.03-10 μM) selectively enhances glutamate-induced calcium influx into human embryonic kidney 293 cells transfected with human GLUA1, GLUA2, GLUA3, or GLUA4 AMPA receptors. LY-503430 also potentiates AMPA-mediated responses in native cortical, hippocampal, and substantia nigra neurons. In Vivo: LY503430 (0.5 mg/kg; s.c; once a day; for 11 days) has functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease. 相关产品：Corticosterone | Dizocilpine maleate | D-AP5 | NMDA | L-Glutamic acid | Evans Blue | CNQX | Kynurenic acid | Glycine | L-Phenylalanine | NBQX | Quinolinic acid | Cycloleucine | Memantine hydrochloride | D-Cycloserine | Ifenprodil tartrate | DNQX | Ro 25-6981 Maleate | Ibotenic acid | (-)-Huperzine A | 24-Hydroxycholesterol | Naspm trihydrochloride | Bupivacaine | Flupirtine Maleate | PEAQX tetrasodium hydrate | Topiramate 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种TOP期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪前沿的制药及生命科学研究进展，为您提供全球前沿的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。