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文献和实验MPEG2000-DSPE是具有一定引湿性的白色粉末状固体,在低级醇、酮、及氯仿中易溶,水中溶解度约(3-4)g/100 ml。 MPEG2000-DSPE分子中聚乙二醇部分分子量约2000,适用于长循环脂质体的制备,使脂质体经静脉注射后不会马上被MPS丰富的组织捕获,从而在血液中循环时间延长,进而增加进入病理组织中的机会。阿霉素脂质体DOXIL中MPEG2000-DSPE的用量占总脂质的20%,与普通阿霉素脂质体Mycoet相比,动力学差异明显。脂质体阿霉素的血浆半衰
How to Make Simple Solutions and Dilutions
of an element or compound, and comprised of exactly 6.023 x 10^23 atoms or molecules (this is called Avagadro''s number). The mole is therefore a unit expressing the amount of a chemical. The mass (g) of one mole of an element is called its molecular weight (MW
Assays for Proteasome Inhibition
with polyubiquitin chains through a cascade of enzyme-catalyzed events. These ‘marked’ proteins are then degraded via the 26S proteasome in an ATP-dependent manner (7 ). The 26S proteasome (EC 3.4.99.46) is a large, multisubunit enzyme (MW=2000 kDa) found in high
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