- ￥13380
- Cedarlane
- CLY200-04AF-100UG
- 2025年07月15日
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文献和实验The CRE Luc Mouse Model for Bioimaging Ligand Activation of G Protein-Coupled Receptors
from a luciferase reporter have been used extensively in vitro with high-throughput screens (HTS) of large chemical compound libraries. We have generated a transgenic mouse model (CRE luc) with a luciferase reporter under the control of a synthetic promoter
Off-Target Networks Derived from Ligand Set Similarity
of drug targets, we calculated the similarity among sets using ligand topology. We developed a statistical model to rank the resulting scores, which were then expressed in minimum spanning trees. We have shown that biologically sensible groups of targets
Flexible Ligand Docking with Glide
for predicting protein?ligand binding modes and ranking ligands via high?throughput virtual screening. Glide utilizes two different scoring functions, SP and XP GlideScore, to rank?order compounds. Three modes of sampling ligand conformational and positional
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