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文献和实验12 Making Fusion Toxins to Target Leukemia and Lymphoma
toxins the connection between the toxin and ligand is encoded by the DNA and not produced by chemical conjugation. Since recombinant toxins must bind specifically to cell surface molecules to kill cells, the number of possible recombinant toxin molecules
Array CGH Reveals Clonal Evolution of Adult T-Cell Leukemia/Lymphoma
Adult T-cell leukemia/lymphoma (ATLL) is the neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1). We performed oligoarray comparative genomic hybridization (CGH) against paired samples comprising peripheral blood (PB) and lymph
Human In-Cell scFv Library from Infiltrating B Cell
to the study of the antibody repertoire formed in vivo during, for example, autoimmune diseases. We describe here, the use of the in-cell PCR together with Cre-recombination applied to human B cells to obtain in situ pairing of the variable (V
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