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文献和实验Use of Activated Natural Killer Cells for Tumor Immunotherapy in Mouse and Human
Natural killer (NK) cells are a subset of lymphocytes with a distinct morphologic appearance (large granular lymphocytes [LGLs]) and the ability to spontaneously kill virally infected or tumor targets but to spare most normal cells
incubator. Longer incubation may occasionally be used, but natural killing should be completed within 4 hours and longer incubation may involve processes other than spontaneous killing (e.g. antibody-mediated cytotoxicity). After the incubation, add
Construction of RibonucleaseAntibody Conjugates for Selective Cytotoxicity
(1 ). Both recombinant RNase fusion proteins (2 –4 see also Chapter 6 , this volume) and chemical RNase conjugates have been made and characterized. The cytotoxic potential of targeted ribonuclease was first demonstrated with bovine RNase conjugated to transferrin
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