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文献和实验Analysis of Human Mitochondrial DNA Mutations
-cytochrome c oxidoreductase), three to Complex IV (cytochrome c oxidase or COX), and two to Complex V (ATP synthase). These subunits are synthesized within the mitochondrion, where they are assembled together with a larger number of subunits encoded
Identification of Mutations in mtDNA from Patients Suffering Mitochondrial Diseases
The human mitochondrial genome. The structural genes for the mtDNA-encoded 12S and 16S ribosomal RNAs, the subunits of NADH-coenzyme Q oxidoreductase (ND), cytochrome-c oxidase (COX), cytochrome-b (Cyt b), and ATP synthase (A), and 22 tRNAs, are shown
(ubiquinol cytochrome c oxido reductase or bc1 complex), IV (cytochrome c oxidase), and V (ATP synthase). These respiratory complexes are conserved from the yeast Saccharomyces cerevisiae to human with the exception of complex I, which is replaced
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