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文献和实验Sequence Similarity Searching Using the BLAST Family of Programs
, J.D., Dubnick, M., Polymeropoulos, M.H., Xiao, H., Merril, C.R., Wu, A., Olde, B., Moreno, R.F., et al. 1991. Complementary DNA sequencing: Expressed sequence tags and human genome project. Science 252:1651‐1656
Using BLAT to Find Sequence Similarity in Closely Related Genomes
a protein sequence to identify the coding regions in a genomic sequence and to search for gene family members in the same species, and using a protein sequence to find homologs in another species. Curr. Protoc. Bioinform. 37:10.8.1?10.8.24. © 2012 by John
Obtaining Comparative Genomic Data with the VISTA Family of Computational Tools
from different species is a fundamental method for identifying functional elements, such as exons or enhancers, as they tend to exhibit significant sequence similarity due to purifying selection. Availability of whole?genome sequences for a constantly growing
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