Abl1 (phospho Tyr204) rabbit pAb

Abl1 (phospho Tyr204) rabbit p

Ab
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  • ¥900
  • AAB
  • 上海
  • A10176
  • 2025年07月12日
  • WB,IHC-p,ELISA
  • Rabbit
  • Human,Mouse,Rat,Monkey
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    • 详细信息
    • 技术资料
    • 免疫原

      The antiserum was produced against synthesized peptide derived from human Abl around the phosphorylation site of Tyr204. AA range:156-205

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse,Rat,Monkey

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      ABL1

    • 抗体英文名

      Abl1 (phospho Tyr204) rabbit pAb

    • 抗体名

      Tyrosine-protein kinase ABL1

    • 规格

      50ul

    ABL proto-oncogene 1, non-receptor tyrosine kinase(ABL1) Homo sapiens This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [pr

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