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Istaroxime oxalate

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  • ¥10600 - 17500
  • TargetMol已认证
  • 美国
  • T69975
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      零下80~20°C

    • 保质期

      Powder: -20°C for 3 years In solvent: -80°C for 2 years

    • 英文名

      Istaroxime oxalate

    • 库存

      10

    • 供应商

      TargetMol

    • CAS号

      203737-94-4

    • 规格

      50 mg/100 mg/25 mg

    规格:50 mg产品价格:¥13800.0
    规格:100 mg产品价格:¥17500.0
    规格:25 mg产品价格:¥10600.0

    Product Introduction
    Bioactivity


    英文名:Istaroxime oxalate

    描述:Istaroxime, also known as PST-2744, is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Na+/K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium/calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy by which intracellular calcium triggers sarcoplasmic reticulum calcium release, and by accelerating the inactivation state of L-type calcium channels, which allow for calcium influx.



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    图标文献和实验
    相关实验
    • Urinary Oxalate and Citrate

      The amounts of oxalate and citrate excreted in urine, and their urinary concentrations are important risk factors for the development of calcium oxalate kidney stones (1 ). The most widely used procedures to estimate these analytes

    • Oxalic Acid

      Oxalate is a common constituent of many plant species. Some crop plants accumulate high levels of this dicarboxylic acid anion (oxalate). Depending on the species, oxalate accumulates primarily as soluble oxalate, insoluble calcium oxalate

    • Cytochrome Oxidase Manometric Analysis

      Materials   0.01 M Potassium Phosphate Buffer, pH 7.4 Sat. K Fe(CN) 0.6 M Sodium Malonate (Malonic acid, sodium salt) 5 mM KCN 0.02% (w/v) p-phenylenediamine oxalate (PPDO)

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