- ￥13900 - 23500
- TargetMol
- 美国
- T69937
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
INCB059872 tosylate
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2081940-67-0
- 规格：
25 mg/100 mg/50 mg
| 规格： | 25 mg | 产品价格： | ￥13900.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥23500.0 |
| 规格： | 50 mg | 产品价格： | ￥18300.0 |
Product Introduction
Bioactivity
英文名:INCB059872 tosylate
描述:INCB059872, also known as INCB59872, is a potent, selective, and orally active lysine-specific demethylase 1 inhibitor. INCB059872 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively, through amine oxidation. LSD1 inhibition enhances H3K4 methylation and increases the expression of tumor-suppressor genes. In addition, LSD1 demethylates mono- or di-methylated H3K9 which increases gene expression of tumor promoting genes; inhibition of LSD1 promotes H3K9 methylation and decreases transcription of these genes.
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文献和实验Nucleoside Modification with Boron Clusters and Their Metal Complexes
Benzene, analytical grade Hexane, analytical grade Pentynyl tosylate (Rong et al
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