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- 保存条件：
4°C, sealed storage, away from moisture
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货期：1-2天
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MedChemExpress LLC
- 规格：
1 mg/5 mg
| 规格： | 1 mg | 产品价格： | ￥3500.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥9500.0 |
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INCB059872 dihydrochloride
MCE 国际站：INCB059872 dihydrochloride
产品活性：INCB059872 dihydrochloride 是一种有效、具有口服活性，选择性和不可逆的赖氨酸特异性去甲基化酶1 (LSD1) 抑制剂。INCB059872 dihydrochloride 可用于髓系白血病的研究。
研究领域：Epigenetics
作用靶点：Histone Demethylase
In Vitro: INCB059872 (25 nM; 48 hours; 293T cells) dihydrochloride increases enhancer activity and gene expression.
INCB059872 (25 nM; 24 hours; THP-1 cells) dihydrochloride makes THP-1 show a growth defect within one cell doubling time or approximately 3 days.
INCB059872 (THP-1 cells) dihydrochloride regulates PRO-seq analysis identifies genes and enhancers.
In Vivo: INCB059872 (10 mg/kg; p.o.; 0, 4, or 6 days; C57BL/6J mice) dihydrochloride makes single-cell RNA-seq revealing changes in bone marrow progenitor populations.
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