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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Adenylyl cyclase type 2 agonist-1
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2414908-52-2
- 规格:
50 mg/25 mg/100 mg
| 规格: | 50 mg | 产品价格: | ¥19400.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥14900.0 |
| 规格: | 100 mg | 产品价格: | ¥24600.0 |
Product Introduction
Bioactivity
英文名:Adenylyl cyclase type 2 agonist-1
描述:Adenylyl cyclase type 2 agonist-1 is a potent agonist of adenylyl cyclase type 2 (AC2) (EC50: 90 nM). It is a potential lead compound in the fight against respiratory diseases.

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文献和实验, in which GTP-bound a-subunit is dissociated from py-subunits (Fig. lC), resulting in a modulation of the function of effector molecules such as adenylyl cyclase, phospholipases, and cGMP phosphodiesterase (Fig. 1D ). The a-subunit of G protein has inherent high
-binding proteins (Gs/olf) leading to activation of adenylyl cyclase and production of intracellular cAMP. D1R and D5R share high level of amino acid identity in transmembrane (TM) regions. Yet these two GPCR subtypes display distinct ligand binding and G
The Measurement of Cyclic AMP Levels in Biological Preparations
of the second group leads to inhibition of adenylyl cyclase and a reduction in AMP generation. Examples of the latter group include α2 -adrenoceptors, A1 adenosine receptors, D2 dopamine receptors, 5-HT1 type receptors, metabotropic glutamate receptors, and μ
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