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- TargetMol
- 美国
- T63797
- 2025年07月09日
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- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
PDZ1i
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2083618-79-3
- 规格：
100 mg/25 mg/50 mg
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
|---|---|---|---|
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
Product Introduction
Bioactivity
英文名:PDZ1i
描述:PDZ1i is a potent MDA-9/Syntenin-specific inhibitor that crosses the blood-brain barrier. PDZ1i inhibits key GBM (glioblastoma multiforme) signaling, including FAK and EGFRvIII, and reduces MMP secretion.
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文献和实验Detection and Characterization of Receptor Interactions with PDZ Domains
Many transmembrane receptors are regulated by associations with scaffold proteins containing PDZ domains, which interact with receptor carboxyl-termini to control receptor signaling, trafficking, and localization. We describe here approaches
Clustering Assay for Studying the Interaction of Membrane Proteins with PDZ Domain Proteins
Some membrane proteins must be clustered at target sites to efficiently perform their functions. PDZ domain-containing scaffold proteins bind to the tails of target membrane proteins and promote their localization and clustering on the cell
Analysis of PDZ Domain Interactions Using Yeast Two-Hybrid and Coimmunoprecipitation Assays
The PDZ domain is a protein-protein interaction module that interacts with a C-terminal short peptide motif in its binding partners. A variety of methods have been used to study PDZ domain interactions. This chapter details the two methods
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