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- TargetMol
- 美国
- T17346
- 2025年09月18日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
9-Decyn-1-ol
- 库存：
10
- 供应商：
TargetMol
- CAS号：
17643-36-6
- 规格：
100 mg
Product Introduction
Bioactivity
英文名:9-Decyn-1-ol
描述:9-Decyn-1-ol is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs. It serves as a conjugation agent to combine GDC-0068 and Lenalidomide, resulting in the formation of INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that operates through the PROTAC mechanism. It effectively inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
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文献和实验Ahr transgenic genotyping by PCR
Bradfield Lab, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School http://mcardle.oncology.wisc.edu/bradfield/Ahr-transgenic-genotyping.html Amplify a 600bp fragment using OL638 and OL639
ARNT transgenic genotyping by PCR
Bradfield Lab, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School http://mcardle.oncology.wisc.edu/bradfield/ARNT-transgenic-genotyping.html Amplify a 700bp fragment using OL637 and OL639. Run 10
ARNT Knockout genotyping by PCR
OL855 and OL856. The neomycin gene will only be present in the knockout allele. Progeny will be either +/+, or +/- ( -/- do not survive), so a positive PCR reaction indicates ARNT +/- and a negative PCR indicates ARNT +/+. Run 15 ul
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