- ￥1859
- TargetMol
- 美国
- T14224
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Amino-PEG10-Boc
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1818294-42-6
- 规格：
100 mg
Product Introduction
Bioactivity
英文名:Amino-PEG10-Boc
描述:Amino-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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文献和实验Synthesis of Peptides Using Tert-Butyloxycarbonyl (Boc) as the -Amino Protection Group
The use of the tert -butyloxycarbonyl (Boc) as the N α-amino protecting group in peptide synthesis can be advantageous in several cases, such as synthesis of hydrophobic peptides and peptides containing ester and thioester moieties
Methylated Polyamines as Research Tools
resulted in corresponding di-Boc-amines, which after deprotection gave target β- and γ-MeSpd’s. To prepare α-MeSpd, the starting compound, 3-amino-1-butanol, was converted into N -Cbz-3-amino-1-butyl methanesulfonate, which alkylated putrescine
in size and shape but show variations in aromatic, electrostatic, and hydrogen bonding properties. These variations provide opportunities to study properties of importance for amide bond mimicry. The derivatives are synthesized from protected natural amino
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