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文献和实验Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
by purification of selected phage by ELISA. Alternatively, there is a bead?based affinity selection method. These methods allow one to readily isolate peptide ligands that bind to a protein target of interest and use the consensus sequence to search proteomic
identified two proteins found in more abundance in these cells as proSAAS and Ephrin type A receptor 2.
Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
to their receptor (6 ). Blocking the interaction between IGFs and their receptors can abolish IGF-stimulated proliferation of lung cancer cells (7 ,8 ). IGFBP-3 is the principal IGFBP in the circulation.
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