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- 库存:
999
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250 ug
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文献和实验IP3受体是一种内质网通道蛋白, 由四个相对分子质量为260kDa的糖蛋白组成的四聚体。四个亚基组成一个跨膜的通道, 每个亚基都有IP3结合的部位, 当3~4个部位被IP3占据时, 受体复合物构象发生改变, 打开离子通道, 储藏在内质网中的Ca2 随即释放,进入胞质溶胶。
Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
a method to evaluate the effect that small molecules have on the binding interactions of a nuclear receptor protein with a series of peptides. The multiplexed microsphere?based system employs peptide?coupled microsphere populations that are fluorescently
Blocking of unwanted non-specific staining
and other cell types. By exploiting the preferential avidity of Fc receptor for human > mouse Ig> rabbit > swine > goat immunoglubulins, one may use a blocking of the receptors with a reagent which will not interfere with the secondary reagents
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