成纤维细胞生长因子21(FGF21)单克隆抗体
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成纤维细胞生长因子21(FGF21)单克隆抗体

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  • ¥1
  • CLOUD-CLONE已认证
  • MAC918Hu23
  • 2025年07月09日
  • WB; IHC; ICC; IP.
  • 小鼠
  • Human,人
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      杭州昊鑫生物

    • 库存

      100

    • 靶点

      FGF21

    • 克隆性

      单克隆

    • 保质期

      12个月

    • 抗体英文名

      Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

    • 抗体名

      FGF21)单克隆抗体

    • 标记物

      无标记物

    • 宿主

      小鼠

    • 适应物种

      Human,人

    • 亚型

      IgG2b Kappa

    • 形态

      液体

    • 应用范围

      WB; IHC; ICC; IP.

    • 保存条件

      -20°

    • 浓度

      1mg/mL

    • 规格

      10ul(限杭州地区终端客户)

    成纤维细胞生长因子21(FGF21)单克隆抗体

    Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21)

     

    • 编号MAC918Hu23
    • 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
    • 来源单抗制备
    • 宿主小鼠
    • 效价(克隆号)C6
    • Ig亚型IgG2b Kappa
    • 纯化方式蛋白A + 蛋白G亲和纯化
    • 标记物无标记物
    • 免疫原RPC918Hu01-成纤维细胞生长因子21(FGF21)重组蛋白
    • 缓冲液成份0.01M 磷酸盐缓冲液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
    • 性状液体
    • 浓度1mg/mL
    • 且适物种-
    • 应用WB; IHC; ICC; IP.
    • 下载英文说明书   中文说明书

    特异性

    该抗体是针对FGF21的小鼠单克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别FGF21。

    用法

    Western blotting: 0.5-2µg/mL;
    Immunohistochemistry: 5-20µg/mL;
    Immunocytochemistry: 5-20µg/mL;
    Optimal working dilutions must be determined by end user.

    储存

    经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

    稳定性

    热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

     

    参考文献

    杂志 参考文献
    Lipids in Health and Disease Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [Lipidworld: source]
    Endocrinology Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression [Endocrine:Source]
    Biochemical and Biophysical Research Communications Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH [Pubmed:25449271]
    Free Radic Biol Med Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway [PubMed: 25843656]
    Journal of diabetes and its complications Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. [pubmed:27916484]
    American journal of the medical sciences Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus [pubmed:29078839]
    Frontiers in Physiology Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 [Pubmed:29593555]
      Некоторые аспекты транспортной системы метаболизма железа в зависимости от степени синдрома перегрузки железом у детей с хроническим … []
    Physiol Res Fibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease. [Pubmed: 32469231]
    Chinese Journal of Osteoporosis 2 型糖尿病患者血清FGF21, 骨连结蛋白和骨转换指标的相关性研究. []
    Sci Rep Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats [33833309]
    Nutrients The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose []
    Medicine (Baltimore) Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort [34918690]
    Annals of Agricultural and Environmental Medicine Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis [34969228]
    J Magn Reson Imaging Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver … [Pubmed:35212074]
    Lab Invest Fibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury [Pubmed:35488034]
    Molecular Biology Reports Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … [Pubmed:35585377]
      High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients []

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    图标文献和实验
    该产品被引用文献

    参考文献

    杂志参考文献
    Lipids in Health and DiseaseDietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs [Lipidworld: source]
    EndocrinologyOrphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression [Endocrine:Source]
    Biochemical and Biophysical Research CommunicationsAlpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH [Pubmed:25449271]
    Free Radic Biol MedSkeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway [PubMed: 25843656]
    Journal of diabetes and its complicationsAssociations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. [pubmed:27916484]
    American journal of the medical sciencesAssociation of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus [pubmed:29078839]
    Frontiers in PhysiologyIleal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21 [Pubmed:29593555]
     Некоторые аспекты транспортной системы метаболизма железа в зависимости от степени синдрома перегрузки железом у детей с хроническим … []
    Physiol ResFibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease. [Pubmed: 32469231]
    Chinese Journal of Osteoporosis2 型糖尿病患者血清FGF21, 骨连结蛋白和骨转换指标的相关性研究. []
    Sci RepIleal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats [33833309]
    NutrientsThe Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose []
    Medicine (Baltimore)Association of serum fibroblast growth factor 21 with kidney function in a population-based Chinese cohort [34918690]
    Annals of Agricultural and Environmental MedicineOxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis [34969228]
    J Magn Reson ImagingWater Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver … [Pubmed:35212074]
    Lab InvestFibroblast growth factor 21, a stress regulator, inhibits Drp1 activation to alleviate skeletal muscle ischemia/reperfusion injury [Pubmed:35488034]
    Molecular Biology ReportsUmbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … [Pubmed:35585377]
     High Circulating Fibroblast Growth Factor-21 Levels as a Prognostic Marker in Fatty Pancreas Patients []
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