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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
peptide
- 亚型:
IgG1
- 形态:
Liquid
- 保存条件:
-20℃
- 克隆性:
mAb
- 适应物种:
Human
- 保质期:
1年
- 目录编号:
TD-32065
- 级别:
科研级
- 库存:
88
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
FCM、ELISA
- 靶点:
详询
- 抗体英文名:
Mouse Monoclonal Antibody to CD51
- 抗体名:
CD51
- 规格:
100ul/50ul
| 规格: | 100ul | 产品价格: | ¥2180.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥1280.0 |
Mouse Monoclonal Antibody to CD51
Description | |
| The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. | |
Specification | |
| Aliases | ITGAV; MSK8; VNRA; VTNR |
| Entrez GeneID | 3685 |
| Swissprot | P06756 |
| clone | 3H1A5 |
| WB Predicted band size | 116kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD51 (AA: extra 31-189) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image | |
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文献和实验CD51 分子 CD51 常用单克隆抗体或代号: 13C2,23C6,NK1- M7;(VNRa 链,integrin a V) 主要表达细胞: Pt,En,Meg [Pt] 分子质量(kDa)和结构: gp150,与CD61组成二聚体 功 能: 粘附VN、FN和vWF CD51 Aka vitronectin receptor-alpha chain; beta chain
整合素家族迟现抗原组 ( β 1 组 ) β1(CD29)整合素亚单位可与CD49α~f(Mα1~α6)、CD51(αV)以及α7~α11分别组成VLAl~VLA6,αV61(VNR-191),α7α1、α8βl、α9β1和α11β1整合素分子。由于最早发现的~%A-1和VLA-2分子是在用同种异体抗原或外源凝集素活化淋巴细胞后数周才出现,因此习惯称为迟现抗原(verylateanngen,VLA)。CD29表达十分广泛,包括所有的白细胞。CD29在记忆T细胞上的表达水平高于
49e/CD29、CD49f/CD29、CD51/CD29、CD11a/CD18、CD11b/CD18、CD11c/CD18、CD41/CD61、CD51/CD61、CD49f/CD104、CD2、CD4、CD8、CD28、CD31、CD50、CD54、CD56、CD58、CD80、CD102、CD106、CD62L、CD62P、CD62E、CD15、CD15s、CD44等。 (2)B表示CD命名范围中属IGSF结构的分子,如CD79a、CD79b、CD1、CD
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