重组人MMP-2

重组人MMP-2 英文名称：Recombinant Human MMP-2 规格：2ug 价格：￥1,128 货号：420-02-2ug RUO PROTEINS Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant Human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids). Source: E.coli Synonyms: Matrix Metalloproteinase-2, Gelatinase A, TBE-1 AA Sequence: MYNFFPRKPK WDKNQITYRI IGYTPDLDPE TVDDAFARAF QVWSDVTPLR FSRIHDGEAD IMINFGRWEH GDGYPFDGKD GLLAHAFAPG TGVGGDSHFD DDELWTLGEG QVVRVKYGNA DGEYCKFPFL FNGKEYNSCT DTGRSDGFLW CSTTYNFEKD GKYGFCPHEA LFTMGGNAEG QPCKFPFRFQ GTSYDSCTTE GRTDGYRWCG TTEDYDRDKK YGFCPETAMS TVGGNSEGAP CVFPFTFLGN KYESCTSAGR SDGKMWCATT ANYDDDRKWG FCPDQGYSLF LVAAHEFGHA MGLEHSQDPG ALMAPIYTYT KNFRLSQDDI KGIQELYGAS PDIDLGTGPT PTLGPVTPEI CKQDIVFDGI AQIRGEIFFF KDRFIWRTVT PRDKPMGPLL VATFWPELPE KIDAVYEAPQ EEKAVFFAGN EYWIYSASTL ERGYPKPLTS LGLPPDVQRV DAAFNWSKNK KTYIFAGDKF WRYNEVKKKM DPGFPKLIAD AWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL GC Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: MMP-2 activity was measured by its ability to cleave a chromogenic peptide MMP-2 substrate at room temperature. At an MMP-2 concentration of 2.5 μg/ml, 50% cleavage was achieved at an incubation time of approximately 25 minutes. Recombinant Human MMP-2 Biological Activity Graph Calculated Molecular Weight: 62 kDa Accession Number: P08253 Gene ID: 4313 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse,重组人MMP-2 是齐一生物公司重点推广产品，齐一生物代理PeproTech的产品原装正品质量，我公司有专业的人员进行全程指导，请放心购买、发货时均会附上质检报告单、使用说明书和推荐用法用量、提供正规发票欢迎来电咨询！ PeproTech于1988年创立于美国，Peprotech的产品具有很高的性价比，这些细胞因子应用于生命科学研究；在众多高水平的实验室和研究机构中广泛使用。截至2013年底，已被13,000篇SCI文献引用；取得了细胞因子产品领域居于地位。 PeproTech重组蛋白与科学服务领域是由经验丰富的蛋白质科学家开发出来的，因此能够为制备抗体提供高品质的原料。重组蛋白到抗原亲和纯化的抗体拥有自己的研发系统，能够保证产品的高品质。