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- 文献和实验
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- 保存条件:
-20°C储存;避免反复冻融
- 英文名:
Recombinant Human IL-12 Protein
- 供应商:
上海阿拉丁生化科技股份有限公司
设定黄金标准,在阿拉丁,我们不仅相信保持质量,而且相信质量。 我们的目标是定义它。 我们的质量管理理念为业界研究试剂建立了高质量的标准。 当您听到阿拉丁这个名字时,就会知道它是各个方面坚定不移品质的灯塔。
说明:产品表货号最后一段中横杠后的重量为产品的包装规格,例如A123456-500g,该货号对应的包装规格为500g。
中文名:Recombinant Human IL-12 Protein
英文名:Recombinant Human IL-12 Protein
中文别名:重组人白细胞介素-12蛋白; CLMF;CLMF p35;CLMF p40;CLMF1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL12; IL-12; IL-12, subunit p35; IL12A; interleukin 12, p35; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; natural killer cell stimulatory factor 1, 35 kD subunit; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; NKSF1; p35
英文别名:CLMF;CLMF p35;CLMF p40;CLMF1; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL12; IL-12; IL-12, subunit p35; IL12A; interleukin 12, p35; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; natural killer cell stimulatory factor 1, 35 kD subunit; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; NKSF1; p35
纯度:ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
cas号:-
产品介绍:
白细胞介素-12 (IL-12)是一个70 kDa(p70蛋白)的异源二聚体细胞因子,由p35 (35 kDa) α 链和p40 (40 kDa) β 链两个共价连接的亚基组成。相对于p35链,p40链被过度生产,并形成同二聚体,与IL-12受体,与具有生物活性的p70异质二聚体竞争受体占用,从而作为受体拮抗剂。IL-12主要由活化的树突状细胞(DCs)、巨噬细胞和中性粒细胞在T细胞启动过程中产生,并直接作用于其细胞毒性免疫效应细胞,包括自然杀伤(NK)细胞、自然杀伤T (NKT)细胞及CD8+ T细胞,以刺激其增殖及增加其细胞毒性功能。IL-12被广泛认为是Th1反应的重要调节因子。它还促进激活的t细胞和NK细胞的扩增和存活,并调节ctl和NK细胞的细胞毒性活性。在适应性免疫应答过程中,IL-12启动抗原特异性t细胞以产生大量IFN-g(促使它们向Th-1通路)。IL-12还可以作为体液免疫的佐剂,通过增强IgG2a和IgG2b抗体的产生。重组人IL-12是一种69-75kDa的异二聚体糖蛋白(共503个氨基酸残基),由35 kDa (p35)和40 kDa组成(p40)由二硫键连接的亚基。
| 货号(SKU): | 纯度: | 价格: | 库存: |
| rp147384-1mg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) | 21099.9 | 0 |
| rp184356-1mg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 16999.9 | 0 |
| rp156174-1mg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 16999.9 | 0 |
| rp184356-100μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 3999.9 | 2 |
| rp156174-100μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 3999.9 | 0 |
| rp147384-100μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) | 3499.9 | 0 |
| rp184356-50μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 2499.9 | 3 |
| rp156174-50μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 2499.9 | 0 |
| rp147384-50μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) | 2189.9 | 0 |
| rp147384-20μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) | 1429.9 | 0 |
| rp147384-10μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE) | 959.9 | 0 |
| rp184356-10μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 799.9 | 23 |
| rp156174-10μg | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥90%(SDS-PAGE) | 799.9 | 10 |
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