- ￥0
- Biorbyt
- 英国
- orb2279051
- 2026年08月07日
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- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
NH2-methylpropanamide-Exatecan TFA
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
1817857-35-4
- 规格：
5 mg/50 mg
| 规格： | 5 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥0.0 |
类别: Small Molecules
描述: Exatecan TFA is a methylpropanamide-modified derivative of the cytotoxin Exatecan, functioning as a potent DNA topoisomerase I inhibitor with an IC50 of 2.2 µM. It is widely used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy research, applicable in both in vitro biochemical assays and in vivo preclinical studies.
靶点: Topoisomerase,ADC Cytotoxin
分子式: C30H30F4N4O7
分子量: 634.58
SMILES: C(C(O)=O)(F)(F)F.N(C([C@H](CN)C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
研究领域: Immunology & Inflammation; Pharmacology & Drug Discovery, Molecular Biology
保存条件: -20°C
备注: For research use only.
描述: Exatecan TFA is a methylpropanamide-modified derivative of the cytotoxin Exatecan, functioning as a potent DNA topoisomerase I inhibitor with an IC50 of 2.2 µM. It is widely used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy research, applicable in both in vitro biochemical assays and in vivo preclinical studies.
靶点: Topoisomerase,ADC Cytotoxin
分子式: C30H30F4N4O7
分子量: 634.58
SMILES: C(C(O)=O)(F)(F)F.N(C([C@H](CN)C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
研究领域: Immunology & Inflammation; Pharmacology & Drug Discovery, Molecular Biology
保存条件: -20°C
备注: For research use only.
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NH2-methylpropanamide-Exatecan TFA，orb2279051，Biorbyt
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