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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
Antibacterial agent 144
- 库存:
99
- 供应商:
Biorbyt
- 规格:
50 mg/5 mg
| 规格: | 50 mg | 产品价格: | ¥0.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥0.0 |
描述: Antibacterial Agent 144 (8e) demonstrates potent activity against multidrug-resistant S. aureus by disrupting the cell membrane and inhibiting biofilms. Its efficacy is further enhanced through HSA binding (Kd=13.2 µM) and DNA complexation, which impedes replication. This profile supports its investigation in antimicrobial research for both in vitro and in vivo applications.
靶点: Others,DNA/RNA Synthesis,Antibacterial
分子式: C26H23N7O3
分子量: 481.51
研究领域: Cell Biology, Infectious Disease & Virology, Molecular Biology
保存条件: -20°C
备注: For research use only.
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文献和实验Genomic Approaches to Antibacterial Discovery
of concept in curing experimental infections. The second approach is based on screening for compounds with antibacterial activity and then employing a broad variety of newer technologies to identify the molecular target of the antibacterial agent
Methods to Assay Inhibitors of tRNA Synthetase Activity
could be a potential antibacterial agent. Only one aa-RS inhibitor, the Ile-RS inhibitor mupirocin, is currently marketed as an antibacterial agent. We focused on phenylalanyl (Phe)-tRNA synthetase (Phe-RS), but the described methods are not restricted to Phe-RS
Assessing the Activity of Bacterial Multidrug Efflux Pumps
Resistance to antibiotics in target bacterial populations has long complicated antibacterial chemotherapy. First described in the early 1980s (1 , 2 ), efflux mechanism of resistance, whereby the antibiotic is actively (i.e., in an energy
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