Antitumor agent-150

Antitumor agent-150 产品活性：Antitumor agent-150 (V10) 是一种抗乳腺癌剂，是 MDM2 的 PROTAC 降解剂（Red: Ganoderic acid A ; Black: 4O-PEG linker; Blue: VHL ligand）。 产品来源： www.medchemexpress.cn/antitumor-agent-150.html 研究领域：PROTAC | Apoptosis 作用靶点：PROTACs | MDM-2/p53 | Apoptosis In Vitro: Antitumor agent-150 (V10) exhibits good tumor inhibitory activity in xenografted TNBC zebrafish models with an inhibition rate of 27.2% at 50 μg/mL. Antitumor agent-150 (V10, 10 μM) promotes apoptosis of MDA-MB-231 cells. Antitumor agent-150 (V10) treatment significantly changes the G1 phase and S phase of MDA-MB-231 cells. 相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E | DAPT