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- 文献和实验
- 技术资料
- 保存条件:
蛋白表达区间:Glu22-Lys236
- 保质期:
See instructions
- 英文名:
标签:C-6His
- 库存:
表达系统:Human Cells
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥720.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2000.0 |
| 规格: | 500ug | 产品价格: | ¥8960.0 |
| 规格: | 1mg | 产品价格: | ¥12800.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.
-67 antigen. ref: 1. Gerdes J, Schwab U, Lemke H, Stein H. 1983. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31:13–20. 2. The Ki-67 Protein
意义: l CCP抗体是早期诊断类风湿性关节炎(RA)的特异性指标,临床敏感性67-80%,特异性大于96%。与类风湿因子的诊断敏感性相当,但特异性更高。 l CCP抗体有助于类风湿关节炎的早期诊断:该抗体可先于疾病的临床表现出现,可以出现在RA典型临床症状的数年前,阳性比RF出现早,特异性比RF高,与联合RF检测,可以提高RA的实验室检出率。 l CCP抗体有助于确诊血清阴性的RA。 l CCP抗体有助于对早期滑膜炎进行诊断与鉴别诊断。 l
率为1%,平均年发病率为67/10万;幼年类风湿关节炎患病率为0.113%,由于我国尚未大范围进行RA的流行病学调查,仅在几个局部地区进行了抽样调查,结果表明,RA在中国的患病率为0.34%-0.5%。 类风关是一种慢性的全身性疾病,以慢性、对称性、多滑膜关节炎和关节外病变为主要临床表现,且发病两年内即可出现不可逆性骨关节破坏, 从而造成肢体部分残废和生活质量下降;发病早期,可利用免疫抑制剂控制病情进展, 阻止关节破坏,而一旦错过治疗窗口期,则只能缓解症状,基本很难阻止病情的恶化。 因此, 类风
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