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Mouse IL-2RA(CK67)

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  • ¥720 - 12800
  • SinoBio
  • 国产
  • CK67
  • 2025年10月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Glu22-Lys236

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥720.0
    规格:50ug产品价格:¥2000.0
    规格:500ug产品价格:¥8960.0
    规格:1mg产品价格:¥12800.0
    产品描述
    Recombinant Mouse Interleukin-2 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Lys236 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    P01590
    产品别称
    CD25; IL-2 R alpha; IL2RA; CD25 antigen; IDDM10; IL-2 receptor subunit alpha; IL2R; IL-2R subunit alpha; IL-2-RA; IL2-RA; interleukin 2 receptor; alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
    偶联
    Unconjugated
    分子量
    25.5 KDa
    表观分子量
    40-60 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.

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    图标文献和实验
    该产品被引用文献

    The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.

    相关实验
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      -67 antigen. ref: 1. Gerdes J, Schwab U, Lemke H, Stein H. 1983. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31:13–20. 2. The Ki-67 Protein

    • 早期诊断RA的重要指标--CCP抗体

      意义: l CCP抗体是早期诊断类风湿性关节炎(RA)的特异性指标,临床敏感性67-80%,特异性大于96%。与类风湿因子的诊断敏感性相当,但特异性更高。 l CCP抗体有助于类风湿关节炎的早期诊断:该抗体可先于疾病的临床表现出现,可以出现在RA典型临床症状的数年前,阳性比RF出现早,特异性比RF高,与联合RF检测,可以提高RA的实验室检出率。 l CCP抗体有助于确诊血清阴性的RA。 l CCP抗体有助于对早期滑膜炎进行诊断与鉴别诊断。 l

    • RA流行病学调查的最新手段:CCP金标快速检测

      率为1%,平均年发病率为67/10万;幼年类风湿关节炎患病率为0.113%,由于我国尚未大范围进行RA的流行病学调查,仅在几个局部地区进行了抽样调查,结果表明,RA在中国的患病率为0.34%-0.5%。 类风关是一种慢性的全身性疾病,以慢性、对称性、多滑膜关节炎和关节外病变为主要临床表现,且发病两年内即可出现不可逆性骨关节破坏, 从而造成肢体部分残废和生活质量下降;发病早期,可利用免疫抑制剂控制病情进展, 阻止关节破坏,而一旦错过治疗窗口期,则只能缓解症状,基本很难阻止病情的恶化。 因此, 类风

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    文献支持
    Mouse IL-2RA(CK67)
    ¥720 - 12800